{"id":3572,"date":"2026-07-16T19:46:17","date_gmt":"2026-07-16T19:46:17","guid":{"rendered":"https:\/\/crosscountrymovingteams.com\/?p=3572"},"modified":"2026-07-16T19:46:17","modified_gmt":"2026-07-16T19:46:17","slug":"the-cholesterol-shot-you-couldnt-afford-is-now-a-pill","status":"publish","type":"post","link":"https:\/\/crosscountrymovingteams.com\/?p=3572","title":{"rendered":"The cholesterol shot you couldn\u2019t afford is now a pill"},"content":{"rendered":"
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The drug\u00a0from Merck was OK\u2019d on Thursday for patients with artery-clogging cholesterol that persists even after taking statins, the standard medications for cutting heart attack risk. Merck will market its pill under the brand name Lipfendra.<\/p>\n

Read more Europe\u00a0optimized\u00a0its supply chains for cost. Now it must pay for resilience<\/a><\/p>\n

It\u2019s the first noninjectable medication that works by blocking a liver protein called PCSK9. That protein limits the body\u2019s ability to clear cholesterol from the blood, and\u00a0biotech injectables\u00a0targeting it have been available from Amgen and other drugmakers for more than a decade. But patient access has been stymied for years by high prices, insurance restrictions and limited prescribing by doctors.<\/p>\n

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Statins block some of the liver\u2019s production of cholesterol and are the cornerstone of treatment. But even at the highest doses, many people need additional help lowering their LDL, or bad, cholesterol enough to meet medical guidelines.<\/p>\n

Merck, which has headquarters in Rahway, New Jersey, won approval based on two studies in high-risk patients who added the company\u2019s pill to their standard treatment, including statins. In one study of 3,000 patients, those taking Lipfendra saw their levels of LDL cholesterol drop more than 55% after six months. In a second study, patients averaged a reduction of 59% compared with patients who received a dummy pill.<\/p>\n

That benefit dropped only slightly over a year, and side effects \u2014 including dizziness and diarrhea \u2014 were similar between those taking the pill or a placebo, researchers found. One caveat: The pill must be taken on an empty stomach.<\/p>\n

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The FDA reviewed the drug under its program that promises\u00a0ultra-fast reviews\u00a0for promising medications that serve the public interest. The pathway was created by then-FDA chief Dr. Marty Makary, who\u00a0resigned from the agency\u00a0in May after months of pressure from drugmakers, patients and other outside groups.<\/p>\n

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Heart disease is the nation\u2019s leading cause of death, and high LDL cholesterol, which causes plaque to build up in arteries, is a top risk factor for heart attacks and strokes. While an LDL level of 100 is considered fine for healthy people, doctors recommend lowering it to at least 70 once people develop high cholesterol or heart disease \u2014 and even lower for those at very high risk.<\/p>\n

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The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute\u2019s Department of Science Education and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.<\/p>\n

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The drug\u00a0from Merck was OK\u2019d on Thursday for patients with artery-clogging cholesterol that persists even after taking statins,<\/p>\n","protected":false},"author":1,"featured_media":43,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3572","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-interesting"],"yoast_head":"\nThe cholesterol shot you couldn\u2019t afford is now a pill - Cross Country Moving Team<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/crosscountrymovingteams.com\/?p=3572\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The cholesterol shot you couldn\u2019t afford is now a pill - Cross Country Moving Team\" \/>\n<meta property=\"og:description\" content=\"The drug\u00a0from Merck was OK\u2019d on Thursday for patients with artery-clogging cholesterol that persists even after taking statins,\" \/>\n<meta property=\"og:url\" content=\"https:\/\/crosscountrymovingteams.com\/?p=3572\" \/>\n<meta property=\"og:site_name\" content=\"Cross Country Moving Team\" \/>\n<meta property=\"article:published_time\" content=\"2026-07-16T19:46:17+00:00\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572\"},\"author\":{\"name\":\"admin\",\"@id\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/#\\\/schema\\\/person\\\/1b8121bfb9a1c55d1fff3fca675fceaa\"},\"headline\":\"The cholesterol shot you couldn\u2019t afford is now a pill\",\"datePublished\":\"2026-07-16T19:46:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572\"},\"wordCount\":452,\"commentCount\":0,\"image\":{\"@id\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/wp-content\\\/uploads\\\/2026\\\/05\\\/175605f33de86f2443ba4177dfff3799.webp\",\"articleSection\":[\"Interesting\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572\",\"url\":\"https:\\\/\\\/crosscountrymovingteams.com\\\/?p=3572\",\"name\":\"The cholesterol shot you couldn\u2019t afford is now a pill - 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